Interpol agent Louis Salinger (Clive Owen) and Manhattan Assistant District Attorney Eleanor Whitman (Naomi Watts) are determined to bring to justice one of the world's most powerful banks, the International Bank of Business and Credit (IBBC) which funds terrorist activities. Uncovering illegal activities including money laundering, arms trading, and the destabilization of governments, Salinger's and Whitman's investigation takes them from Berlin to Milan, where the IBBC assassinates Umberto Calvini, an Italian prime ministerial candidate. Following a lead on the assassin to New York City, Salinger is involved in a gunfight in the Solomon R. Guggenheim Museum. An ally of Salinger in the NYPD tracks down the assassin's handler Wexler, who helps Salinger reach Istanbul, where the CEO of the IBBC is conducting an arms deal. Both Wexler and Skarssen are killed by a hitman contracted by Enzo and Mario Calvini to avenge their father's murder by the bank. Salinger is left stunned; his investigation, pursuit and determination having lead him to nothing. However, during the credits, it is indicated that the bank continues with its plans and is successful, despite the death of its CEO. Pre–release trailers indicate that a source for the drama may be found in the quasi-historical corporate entity known as Permindex and the defunct Bank of Credit and Commerce International.
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